Pyrithione
Product Specifications
UNSPSC Description
Pyrithione, a Transition metal complexe, is a zinc ionophore that causes increased zinc levels within mammalian cells. Pyrithione has potent bactericidal and anti-fungal activity[1][2].
Target Antigen
Bacterial; Fungal
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/pyrithione.html
Purity
99.75
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
S=C1C=CC=CN1O
Molecular Weight
127.16
References & Citations
[1]PANSY FE, et al. In vitro studies with 1-hydroxy-2(1H) pyridinethione. Proc Soc Exp Biol Med. 1953 Jan;82(1):122-4.|[2]Nancy L Reeder, et al. Zinc pyrithione inhibits yeast growth through copper influx and inactivation of iron-sulfur proteins. Antimicrob Agents Chemother. 2011 Dec;55(12):5753-60.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-B1747/Pyrithione-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-B1747/Pyrithione-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1121-30-8
Available Sizes
Curated Selection
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