Pyrithione

Pyrithione is an inhibitor of membrane transport processes in fungi. Pyrithione is a potent antibiotic aspergillic acid. Pyrithion incubated Penicillium mycelia would have a marked decrease in the activities of a variety of independently regulated transport systems[1].

Product Specifications

CAS Number

[1121-30-8]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Antibiotic; Bacterial; Fungal

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/pyrithione.html

Purity

99.75

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

S=C1C=CC=CN1O

Molecular Formula

C5H5NOS

Molecular Weight

127.16

Precautions

H302, H315, H319, H335

References & Citations

[1]Chandler, C. J., & Segel, I. H. (1978) . Mechanism of the antimicrobial action of pyrithione: effects on membrane transport, ATP levels, and protein synthesis. Antimicrobial agents and chemotherapy, 14 (1), 60–68.