Linetastine
Linetastine (TMK-688) is a dual-action small molecule that functions as a 5-lipoxygenase (5-LOX) inhibitor, suppressing leukotriene synthesis, and as a histamine receptor antagonist. Its research applications include studies in asthma, atherosclerosis, and peptic ulcer disease, with utility in both in vitro enzymatic assays and in vivo inflammatory models.
Product Specifications
CAS Number
159776-68-8
Product Name Alternative
5-LOX, Histamine Receptor, HistamineReceptor, Linetastine, LTR, TMK-688, TMK 688, TMK688
Field of Research
Immunology & Inflammation, Metabolism Research, Neuroscience, Pharmacology & Drug Discovery
Purity
99.55% (May vary between batches)
Solubility
DMSO:50 mg/mL (85.51 mM)
Smiles
C (OC1CCN (CCNC (/C=C/C=C/C2=CC (OC) =C (OC (OCC) =O) C=C2) =O) CC1) (C3=CC=CC=C3) C4=CC=CC=C4
Molecular Formula
C35H40N2O6
Molecular Weight
584.7
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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