Poloxin-2
Poloxin-2 is a potent and selective inhibitor targeting the Polo-box domain (PBD) of Polo-like kinase 1 (Plk1) . It demonstrates anti-tumor activity by reducing Plk1 protein levels in HeLa cells and has been utilized in vitro to study mitosis, cell cycle progression, and cancer therapeutics.
Product Specifications
CAS Number
321695-37-8
Product Name Alternative
PLK1, Poloxin2, Poloxin-2, Poloxin 2
Field of Research
Cell Biology
Purity
99.59% (May vary between batches)
Solubility
DMSO:12.5 mg/mL (46.42 mM)
Smiles
N (OC (=O) C1=C (C) C=CC=C1) =C2C (C) =CC (=O) C (C) =C2
Molecular Formula
C16H15NO3
Molecular Weight
269.3
Storage Conditions
-20°C
Notes
For research use only.