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ABT-281

ABT-281 is a topical ascomycin-derived macrolactam that potently inhibits T-cell activation. Its optimized profile minimizes systemic exposure, making it a valuable research tool for studying localized immune responses in dermatological and inflammatory disease models, both in vitro and in vivo.

Product Specifications

CAS Number

148147-65-3

Smiles

[H][C@]12O[C@] (O) ([C@H] (C) C[C@@H]1OC) C (=O) C (=O) N1CCCC[C@@]1 ([H]) C (=O) O[C@@H] ([C@H] (C) [C@@H] (O) CC (=O) [C@H] (CC) \C=C (C) \C[C@H] (C) C[C@@H]2OC) C (\C) =C/[C@@H]1CC[C@@H] ([C@@H] (C1) OC) n1cnnn1 |c:38|

Molecular Formula

C44H69N5O11

Molecular Weight

844.06

Storage Conditions

-20°C

Notes

For research use only.

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