AC-186
AC-186 is a selective nonsteroidal agonist for estrogen receptor β (ERβ), exhibiting high affinity for ERβ (EC50 = 6 nM) over ERα (EC50 = 5000 nM) . Its neuroprotective properties have been demonstrated in research models, supporting its use in studying neurodegenerative conditions such as Parkinson's disease.
Product Specifications
CAS Number
1421854-16-1
Product Name Alternative
AC186, AC-186, AC 186, ER, Estrogen Receptor, EstrogenReceptor, progestogen Receptor, progestogenReceptor
Field of Research
Metabolism Research
Purity
99.53% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (10.77 mM) ; DMSO:80 mg/mL (261.16 mM)
Smiles
FC=1C=CC=CC1C2 (C3=CC=C (O) C=C3) CCC (F) (F) CC2
Molecular Formula
C18H17F3O
Molecular Weight
306.32
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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