AG311
AG311 is a small molecule that inhibits mitochondrial complex I and blocks HIF-1α stabilization under hypoxia. This action rapidly triggers necrosis in cancer cells via mitochondrial depolarization, superoxide generation, and calcium influx. It serves as a useful research tool for studying cancer metabolism, oxidative stress, and necrotic cell death pathways in vitro.
Product Specifications
CAS Number
1126602-42-3
Field of Research
Cell Biology
Smiles
S (C1=C2C=3C (NC2=CC=C1) =NC (N) =NC3N) C4=CC=C (C) C=C4
Molecular Formula
C17H15N5S
Molecular Weight
321.4
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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