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AM-6761

AM-6761 is a potent small molecule MDM2-p53 interaction inhibitor. It demonstrates significant antitumor efficacy in vivo, with an ED50 of 11 mg/kg in the SJSA-1 osteosarcoma xenograft model, supporting its use in cancer research targeting p53 pathways.

Product Specifications

CAS Number

1584732-36-4

Smiles

[C@H] (CS (C (C) (C) C) (=O) =O) (N1[C@@H] ([C@H] (C[C@@] (CC=2SC (CC (O) =O) =CN2) (C) C1=O) C3=CC (Cl) =CC=C3) C4=CC (F) =C (Cl) C=C4) [C@@H]5CC5

Molecular Formula

C33H37Cl2FN2O5S2

Molecular Weight

695.69

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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