AMG-221
AMG-221 is a potent and selective inhibitor of 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) . In diet-induced obese mice, it reduced fed blood glucose, insulin levels, and body weight. This small molecule is a valuable research tool for studying metabolic disorders, including type 2 diabetes and obesity, in both in vitro and in vivo models.
Product Specifications
CAS Number
1095565-81-3
Field of Research
Metabolism Research
Smiles
N ([C@@H]1[C@@]2 (C[C@] (C1) (CC2) [H]) [H]) C=3S[C@] (C (C) C) (C) C (=O) N3
Molecular Formula
C14H22N2OS
Molecular Weight
266.4
Storage Conditions
-20°C
Notes
For research use only.
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