AZ-4217
AZ-4217 is a potent BACE1 inhibitor with an IC50 of 160 pM in human SH-SY5Y cells. It demonstrates acute central efficacy in vivo, reducing amyloid plaque deposition in models like Tg2576 mice, supporting its use in Alzheimer's disease research.
Product Specifications
CAS Number
1383846-83-0
Field of Research
Neuroscience
Smiles
NC1=N[C@] (C=2C1=C (F) C=CC2) (C3=CN (CC) C (=O) C (C) =C3) C4=CC (=CC=C4) C=5C=C (C#CC) C=NC5
Molecular Formula
C30H25FN4O
Molecular Weight
476.54
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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