Azadirone
Azadirone is a limonoid tetranortriterpene that sensitizes cancer cells to TRAIL-induced apoptosis. It functions by increasing DR4/DR5 expression via ROS-ERK-CHOP signaling while modulating apoptotic and survival proteins. This compound is used in vitro for research in oncology, apoptosis signaling, and chemosensitization studies.
Product Specifications
CAS Number
30002-86-9
Field of Research
Cell Biology, Infectious Disease & Virology
Smiles
[H][C@@]12CO[C@@H] (CN (N=O) C (N) =O) [C@]1 ([H]) OC (C) (C) O2
Molecular Formula
C9H15N3O5
Molecular Weight
245.23
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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