AZD-9164 bromide
AMG-221 is a potent and selective 11β-HSD1 inhibitor, demonstrating sustained 24-hour ex vivo inhibition in adipose tissue. In diet-induced obese mice, it reduced fed blood glucose, insulin levels, and body weight, supporting its research application in metabolic disorders such as type 2 diabetes and obesity.
Product Specifications
CAS Number
1034916-72-7
Field of Research
Neuroscience
Smiles
C (CC1=CC=C (F) C=C1) [N+]23C[C@H] (OC ([C@] (C) (C4=CC=CC=C4) N5CCCCC5) =O) C (CC2) CC3.[Br-]
Molecular Formula
C29H38BrFN2O2
Molecular Weight
545.53
Storage Conditions
-20°C
Notes
For research use only.
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