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AZD-9164 bromide

AMG-221 is a potent and selective 11β-HSD1 inhibitor, demonstrating sustained 24-hour ex vivo inhibition in adipose tissue. In diet-induced obese mice, it reduced fed blood glucose, insulin levels, and body weight, supporting its research application in metabolic disorders such as type 2 diabetes and obesity.

Product Specifications

CAS Number

1034916-72-7

Field of Research

Neuroscience

Smiles

C (CC1=CC=C (F) C=C1) [N+]23C[C@H] (OC ([C@] (C) (C4=CC=CC=C4) N5CCCCC5) =O) C (CC2) CC3.[Br-]

Molecular Formula

C29H38BrFN2O2

Molecular Weight

545.53

Storage Conditions

-20°C

Notes

For research use only.

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