AZ-PFKFB3-67
AZ-PFKFB3-67 is a selective PFKFB3 inhibitor (IC50=11 nM) that suppresses angiogenesis by reducing lactate and ATP in endothelial cells during tube formation. It also lowers MCL-1 levels and demonstrates neuroprotective properties, making it a useful tool for oncology and neurobiology research.
Product Specifications
CAS Number
1704741-11-6
Product Name Alternative
AZPFKFB367, AZ-PFKFB367, AZ-PFKFB-3-67, AZ-PFKFB3-67, AZPFKFB3-67, AZ PFKFB3 67
Field of Research
Cell Biology, Metabolism Research, Signal Transduction
Purity
99.79% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.39 mM) ; DMSO:80 mg/mL (175.63 mM)
Smiles
C (#N) C=1C=2C (N (CC=3C (C) =NOC3C) C1) =CC=C (OC4=CC=C (NC (=O) [C@@H]5CCCN5) C=C4) C2
Molecular Formula
C26H25N5O3
Molecular Weight
455.51
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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