TACC3 (phospho-Ser558) rabbit pAb

This gene encodes a member of the transforming acidic colied-coil protein family. The encoded protein is a motor spindle protein that may play a role in stabilization of the mitotic spindle. This protein may also play a role in growth a differentiation of certain cancer cells. [provided by RefSeq, Nov 2011],

Product Specifications

Background

UniProt

Q9Y6A5

Swiss Prot

Q9Y6A5

Reactivity

Human; Rat; Mouse

Immunogen

Synthesized phosho peptide around human TACC3 (Ser558)

Clonality

Polyclonal

Source

Rabbit

Applications

Concentration

1 mg/ml

Dilution

WB 1:1000-2000

Molecular Weight

80kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

80kD

Fragment

IgG

Subcellular Location

Cytoplasm . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, spindle . Cytoplasm, cytoskeleton, spindle pole . In complex with CKAP5 localized to microtubule plus-ends in mitosis and interphase. In complex with CKAP5 and clathrin localized to inter-microtubule bridges in mitotic spindles. .