C188
C188 is a cell-permeable, small-molecule STAT3 inhibitor that selectively blocks IL-6-induced STAT3 phosphorylation and nuclear translocation by targeting its SH2 domain. It is a valuable research tool for studying STAT3-dependent signaling in cancer and inflammation, with demonstrated utility in both in vitro and in vivo models.
Product Specifications
CAS Number
823828-18-8
Field of Research
Cell Biology, Signal Transduction, Stem Cell & Developmental Biology
Smiles
OC (=O) CSc1cc (NS (=O) (=O) c2ccc (cc2) C (O) =O) c2ccccc2c1O
Molecular Formula
C19H15NO7S2
Molecular Weight
433.45
Storage Conditions
-20°C
Notes
For research use only.
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