CBS-3595
CBS-3595 is a dual p38α MAPK/PDE-4 inhibitor with moderate nanomolar potency, favorable pharmacokinetics, and low plasma protein binding. Its anti-inflammatory efficacy, demonstrated by suppressing TNFα release in vivo, occurs at doses and systemic exposures significantly below toxicological thresholds, supporting its research utility in inflammatory disease models.
Product Specifications
CAS Number
908380-97-2
Field of Research
Metabolism Research, Signal Transduction
Smiles
CN1C (=C (N=C1S (C) =O) C2=CC=C (F) C=C2) C=3C=C (NC (C) =O) N=CC3
Molecular Formula
C18H17FN4O2S
Molecular Weight
372.42
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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