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Ceralasertib formate

Ceralasertib is a selective, orally bioavailable ATR kinase inhibitor that blocks CHK1 phosphorylation, disrupting DNA damage repair and checkpoint signaling to induce apoptosis. It is widely used in preclinical oncology research, both in vitro and in vivo, to investigate synthetic lethality and combination therapies with DNA-damaging agents.

Product Specifications

CAS Number

1352280-98-8

Field of Research

Molecular Biology, Signal Transduction

Smiles

OC=O.C[C@@H]1COCCN1c1cc (nc (n1) -c1ccnc2[nH]ccc12) C1 (CC1) [S@] (C) (=N) =O

Molecular Formula

C21H26N6O4S

Molecular Weight

458.54

Storage Conditions

-20°C

Notes

For research use only.

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