Ceralasertib formate
Ceralasertib is a selective, orally bioavailable ATR kinase inhibitor that blocks CHK1 phosphorylation, disrupting DNA damage repair and checkpoint signaling to induce apoptosis. It is widely used in preclinical oncology research, both in vitro and in vivo, to investigate synthetic lethality and combination therapies with DNA-damaging agents.
Product Specifications
CAS Number
1352280-98-8
Field of Research
Molecular Biology, Signal Transduction
Smiles
OC=O.C[C@@H]1COCCN1c1cc (nc (n1) -c1ccnc2[nH]ccc12) C1 (CC1) [S@] (C) (=N) =O
Molecular Formula
C21H26N6O4S
Molecular Weight
458.54
Storage Conditions
-20°C
Notes
For research use only.
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog