CL075
CL075 (3M002) is a selective Toll-like receptor 8 (TLR8) agonist that activates the MyD88 pathway, leading to NF-κB and IRF7 activation and subsequent induction of pro-inflammatory cytokines and type I interferons. This small molecule is widely used in immunology research to study TLR8 signaling in both cellular assays and animal models of immune response and viral infection.
Product Specifications
CAS Number
256922-53-9
Product Name Alternative
MyD88, NF-kB, NFkB, NF-κB, NFκB, CL 075, CL075, CL-075, 3M 002, 3M002, 3M-002, TLR8
Field of Research
Immunology & Inflammation, Signal Transduction
Purity
99.25% (May vary between batches)
Solubility
DMSO:19.8 mg/mL (81.37 mM)
Smiles
CCCc1nc2c (N) nc3ccccc3c2s1
Molecular Formula
C13H13N3S
Molecular Weight
243.33
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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