CM-414
CM-414 is a dual HDAC and PDE5 inhibitor with potent activity against key isoforms. In Alzheimer's disease models, it reduces Aβ and pTau, enhances synaptic gene expression, and rescues cognitive and neuronal deficits, supporting its use in neurodegenerative disease research.
Product Specifications
CAS Number
1624792-70-6
Field of Research
Epigenetics & Chromatin, Metabolism Research, Molecular Biology
Smiles
C (CC) C=1C2=C (C (=O) N=C (N2) C3=C (OCC) C=CC (C[C@H]4C[C@@H] (C (NO) =O) C4) =C3) N (C) N1
Molecular Formula
C23H29N5O4
Molecular Weight
439.51
Storage Conditions
-20°C
Notes
For research use only.
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