DS-8587
DS-8587 is a DNA topoisomerase inhibitor with potent in vitro activity against quinolone-resistant A. baumannii, including strains with QRDR mutations. Its efficacy is not affected by common efflux pumps, and it demonstrates significant in vivo antibacterial activity in a murine liver abscess model caused by F. necrophorum.
Product Specifications
CAS Number
1356918-39-2
Field of Research
Infectious Disease & Virology
Smiles
CC1=C2N ([C@H]3[C@H] (C3) F) C=C (C (C2=CC (F) =C1N4C[C@@]5 ([C@] (C4) (CCC5) N) F) =O) C (O) =O.Cl.O.O
Molecular Formula
C21H27ClF3N3O5
Molecular Weight
493.90
Storage Conditions
-20°C
Notes
For research use only.
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