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Elismetrep

Elismetrep (MT-8554) is a potent and orally bioavailable TRPM8 channel antagonist. It is utilized in preclinical research to investigate mechanisms of pain and thermoregulation, with studies exploring its potential for alleviating conditions like menopausal hot flashes in vivo.

Product Specifications

CAS Number

1400699-64-0

Product Name Alternative

MT 8554, MT8554, MT-8554, Elismetrep, TRPVChannel, TRPV Channel, TRP Channel, TRPM8, TRPChannel

Field of Research

Pharmacology & Drug Discovery

Purity

99.37% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (6.08 mM) ; DMSO:80 mg/mL (147.46 mM)

Smiles

O=C (O) C1=CC=C (C=C1) S (=O) (=O) N (C=2N=CC3=CC=CC=C3C2C4CC4) CC5=CC=C (OC (F) (F) F) C=C5

Molecular Formula

C27H21F3N2O5S

Molecular Weight

542.53

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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