FR-167356
FR-167356 is a potent and selective inhibitor of the a3 isoform of vacuolar H+-ATPase, demonstrating activity in osteoclast, renal, and macrophage membranes. This compound has been shown to reduce bone metastasis in B16-F10 melanoma models, making it a useful research tool for studying bone biology and cancer metastasis.
Product Specifications
CAS Number
174185-16-1
Product Name Alternative
FR 167356, FR167356, FR-167356, Vacuolar type H+-ATPase
Field of Research
Pharmacology & Drug Discovery
Purity
98.44% (May vary between batches)
Solubility
DMSO:22.5 mg/mL (59.48 mM)
Smiles
C (C) (C) (O) C=1C=2C (=C (NC (=O) C3=C (Cl) C=CC=C3Cl) C=CC2) OC1C
Molecular Formula
C19H17Cl2NO3
Molecular Weight
378.25
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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