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FR-167356

FR-167356 is a potent and selective inhibitor of the a3 isoform of vacuolar H+-ATPase, demonstrating activity in osteoclast, renal, and macrophage membranes. This compound has been shown to reduce bone metastasis in B16-F10 melanoma models, making it a useful research tool for studying bone biology and cancer metastasis.

Product Specifications

CAS Number

174185-16-1

Product Name Alternative

FR 167356, FR167356, FR-167356, Vacuolar type H+-ATPase

Field of Research

Pharmacology & Drug Discovery

Purity

98.44% (May vary between batches)

Solubility

DMSO:22.5 mg/mL (59.48 mM)

Smiles

C (C) (C) (O) C=1C=2C (=C (NC (=O) C3=C (Cl) C=CC=C3Cl) C=CC2) OC1C

Molecular Formula

C19H17Cl2NO3

Molecular Weight

378.25

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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