Furamidine dihydrochloride
Furamidine dihydrochloride is a cell-permeable, selective PRMT1 inhibitor that competitively targets the enzyme's active site. It also exhibits minor groove DNA binding affinity for AT-rich sequences. This compound demonstrates anti-proliferative activity in various leukemia cell lines in vitro, supporting its use in oncology and epigenetics research.
Product Specifications
CAS Number
55368-40-6
Product Name Alternative
Furamidine Dihydrochloride, Furamidine dihydrochloride, Furamidine HCl, Furamidine, NSC305831 dihydrochloride, NSC 305831 dihydrochloride, DB 75, DB75, NSC 305831, WR 199385, DB 75, DB75, NSC 305831, WR199385, DB 75, DB75, NSC 305831, WR-199385, DB75 dihydrochloride
Field of Research
Epigenetics & Chromatin, Infectious Disease & Virology, Metabolism Research
Purity
98.16% (May vary between batches)
Solubility
DMSO:10 mg/mL (26.51 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.65 mM)
Smiles
N=C (C1=CC=C (C2=CC=C (C3=CC=C (C (N) =N) C=C3) O2) C=C1) N.Cl.Cl
Molecular Formula
C18H18Cl2N4O
Molecular Weight
377.27
Storage Conditions
-20°C
Notes
For research use only.
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