GSK270822A
GSK270822A is a potent and selective ROCK1 inhibitor with an IC50 of 9 nM, demonstrating significant selectivity over RSK1 and p70S6K. This small molecule is a valuable research tool for investigating Rho-kinase signaling in cellular models of cardiovascular function, neuronal outgrowth, and cancer cell motility.
Product Specifications
CAS Number
864082-23-5
Product Name Alternative
GRK2, GSK270822A, GSK-270822A, GSK 270822A
Field of Research
Cell Biology, Pharmacology & Drug Discovery, Signal Transduction, Stem Cell & Developmental Biology
Purity
98.13% (May vary between batches)
Solubility
DMSO:50 mg/mL (126.12 mM)
Smiles
C (NC=1C=C2C (=CC1) NN=C2) (=O) C=3C (CC (=O) NC3C) C4=CC5=C (C=C4) C=CC=C5
Molecular Formula
C24H20N4O2
Molecular Weight
396.44
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
375287-01 20 µg
SFTPC, Recombinant, Bovine, aa25-58, His-GST-Tag (Pulmonary Surfactant-associated Protein C)
Sign In for Pricing
View Details 375287-02 100 µg
SFTPC, Recombinant, Bovine, aa25-58, His-GST-Tag (Pulmonary Surfactant-associated Protein C)
Sign In for Pricing
View Details 
MBS2094193-01 0.1 mL
Biotin-Linked Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3)
Sign In for Pricing
View Details MBS2094193-02 0.2 mL
Biotin-Linked Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3)
Sign In for Pricing
View Details MBS2094193-03 0.5 mL
Biotin-Linked Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3)
Sign In for Pricing
View Details MBS2094193-04 1 mL
Biotin-Linked Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3)
Sign In for Pricing
View Details