GSK270822A
GSK270822A is a potent and selective ROCK1 inhibitor with an IC50 of 9 nM, demonstrating significant selectivity over RSK1 and p70S6K. This small molecule is a valuable research tool for investigating Rho-kinase signaling in cellular models of cardiovascular function, neuronal outgrowth, and cancer cell motility.
Product Specifications
CAS Number
864082-23-5
Product Name Alternative
GRK2, GSK270822A, GSK-270822A, GSK 270822A
Field of Research
Cell Biology, Pharmacology & Drug Discovery, Signal Transduction, Stem Cell & Developmental Biology
Purity
98.13% (May vary between batches)
Solubility
DMSO:50 mg/mL (126.12 mM)
Smiles
C (NC=1C=C2C (=CC1) NN=C2) (=O) C=3C (CC (=O) NC3C) C4=CC5=C (C=C4) C=CC=C5
Molecular Formula
C24H20N4O2
Molecular Weight
396.44
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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