GSK299115A
GSK299115A is a potent and selective ROCK1 inhibitor with an IC50 of 8 nM, demonstrating significantly lower activity against RSK1 and p70S6K. This small molecule is a valuable research tool for investigating Rho-kinase signaling in cellular assays and has been utilized in studies exploring vascular function and fibrosis.
Product Specifications
CAS Number
864082-35-9
Product Name Alternative
GSK299115A, GSK-299115A, GSK 299115A, GRK2
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Purity
98.99% (May vary between batches)
Solubility
DMSO:50 mg/mL (120.4 mM)
Smiles
C (NC=1C=C2C (=CC1) NN=C2) (=O) C=3C (CC (=O) NC3C) C4=CC (Cl) =C (Cl) C=C4
Molecular Formula
C20H16Cl2N4O2
Molecular Weight
415.27
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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