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GSK299115A

GSK299115A is a potent and selective ROCK1 inhibitor with an IC50 of 8 nM, demonstrating significantly lower activity against RSK1 and p70S6K. This small molecule is a valuable research tool for investigating Rho-kinase signaling in cellular assays and has been utilized in studies exploring vascular function and fibrosis.

Product Specifications

CAS Number

864082-35-9

Product Name Alternative

GSK299115A, GSK-299115A, GSK 299115A, GRK2

Field of Research

Pharmacology & Drug Discovery, Signal Transduction

Purity

98.99% (May vary between batches)

Solubility

DMSO:50 mg/mL (120.4 mM)

Smiles

C (NC=1C=C2C (=CC1) NN=C2) (=O) C=3C (CC (=O) NC3C) C4=CC (Cl) =C (Cl) C=C4

Molecular Formula

C20H16Cl2N4O2

Molecular Weight

415.27

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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