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HS-438

HS-438 is a research compound that potently targets the BCR-ABL T315I mutant, a common cause of imatinib resistance in chronic myeloid leukemia (CML) . It has demonstrated inhibitory activity in cellular assays and shows promise for investigating novel therapeutic strategies against resistant CML in preclinical models.

Product Specifications

CAS Number

1430720-10-7

Field of Research

Cardiovascular Research, Cell Biology, Signal Transduction

Smiles

N (C (NCCO) =O) C=1SC=2C (N1) =CC=C (C2) C3=C (OC) C=CC=C3

Molecular Formula

C17H17N3O3S

Molecular Weight

343.4

Storage Conditions

-20°C

Notes

For research use only.

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