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IACS-010759 hydrochloride

IACS-010759 hydrochloride is a potent, selective, and orally bioavailable OXPHOS inhibitor. It suppresses proliferation and promotes apoptosis in OXPHOS-dependent cancers, including models of AML and glioblastoma, making it a valuable tool for studying relapsed/refractory malignancies in both in vitro and in vivo experimental settings.

Product Specifications

CAS Number

1807523-99-4

Product Name Alternative

IACS 010759, IACS 010759 hydrochloride, IACS 010759 Hydrochloride, IACS 10759, IACS010759, IACS-010759, IACS010759 HCl, IACS-010759 HCl, IACS010759 hydrochloride, IACS010759 Hydrochloride, IACS-010759 Hydrochloride, IACS10759, IACS-10759, IACS10759 hydrochloride, IACS-10759 hydrochloride

Field of Research

Cell Biology, Metabolism Research

Purity

98.81% (May vary between batches)

Solubility

DMSO:50 mg/mL (83.47 mM) ;2% DMSO+40% PEG300+5% Tween 80+53% Saline:1 mg/mL (1.67 mM) ; H2O:< 1 mg/mL (insoluble)

Smiles

Cl.O=S (=O) (C) C1CCN (C2=CC=CC (=C2) CN3N=C (N=C3C) C4=NC (=NO4) C=5C=CC (OC (F) (F) F) =CC5) CC1

Molecular Formula

C25H26ClF3N6O4S

Molecular Weight

599.03

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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