JG-48
JG-48 is a small molecule Hsp70 inhibitor that reduces both phosphorylated and total Tau protein levels in cellular models, including endogenous Tau in neuroblastoma cells. This compound is a useful research tool for studying tauopathies, such as Alzheimer's disease, in both in vitro and in vivo experimental systems.
Product Specifications
CAS Number
1627122-26-2
Field of Research
Metabolism Research, Signal Transduction
Smiles
CN1/C (/SC=2C1=CC=C (C (F) (F) F) C2) =C\3/C (=O) N (CC) \C (=C\C4=CC=CC=N4) \S3
Molecular Formula
C20H16F3N3OS2
Molecular Weight
435.49
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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