JNJ-46356479
JNJ-46356479 is a selective, orally bioavailable positive allosteric modulator (PAM) of the mGlu2 receptor, exhibiting an EC50 of 78 nM and an Emax of 256%. This compound is a valuable research tool for investigating mGlu2 receptor function in neuropsychiatric disorders, applicable in both in vitro assays and in vivo preclinical models.
Product Specifications
CAS Number
1254979-66-2
Field of Research
Neuroscience
Smiles
C (F) (F) (F) C=1C=2N (C (CC3CC3) =NN2) C=CC1CN4CCN (CC4) C5=C (F) C=C (F) C=C5
Molecular Formula
C22H22F5N5
Molecular Weight
451.44
Storage Conditions
-20°C
Notes
For research use only.
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