K-14585

K-14585 is a selective PAR2 antagonist that inhibits PAR2-mediated NF-κB activation and IL-8 production induced by agonists like SLIGKV. Interestingly, it can elevate IL-8 levels when administered alone. This compound is a valuable research tool for studying PAR2 signaling in inflammation, cancer, and pain models, applicable in both cellular and animal studies.

Product Specifications

CAS Number

880546-17-8

Field of Research

Pharmacology & Drug Discovery, Signal Transduction

Smiles

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