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KB-130015

KB-130015 is described as an activator of hERG1 potassium channels, yet it exhibits a blocking effect on both native and recombinant hERG1 channels at high membrane potentials. This dual-function compound is utilized in cardiac electrophysiology and safety pharmacology research to investigate channel gating, arrhythmia mechanisms, and pro-tumorigenic signaling pathways in vitro.

Product Specifications

CAS Number

147030-48-6

Field of Research

Metabolism Research, Pharmacology & Drug Discovery

Smiles

C (C=1C=2C (OC1C) =CC=CC2) C3=CC (I) =C (OCC (O) =O) C (I) =C3

Molecular Formula

C18H14I2O4

Molecular Weight

548.11

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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