KB-130015
KB-130015 is described as an activator of hERG1 potassium channels, yet it exhibits a blocking effect on both native and recombinant hERG1 channels at high membrane potentials. This dual-function compound is utilized in cardiac electrophysiology and safety pharmacology research to investigate channel gating, arrhythmia mechanisms, and pro-tumorigenic signaling pathways in vitro.
Product Specifications
CAS Number
147030-48-6
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Smiles
C (C=1C=2C (OC1C) =CC=CC2) C3=CC (I) =C (OCC (O) =O) C (I) =C3
Molecular Formula
C18H14I2O4
Molecular Weight
548.11
Storage Conditions
-20°C
Notes
For research use only.
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