KBP-7018
KBP-7018 is a potent and selective small molecule inhibitor targeting the fibrotic kinases c-KIT, RET, and PDGFR with IC50 values of 10 nM, 7.6 nM, and 25 nM, respectively. It is a valuable research tool for investigating fibrotic pathways and has demonstrated anti-fibrotic efficacy in preclinical in vivo models of systemic sclerosis and pulmonary fibrosis.
Product Specifications
CAS Number
1613437-66-3
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Purity
99.73% (May vary between batches)
Smiles
C (\NC=1C=C2C (=CC1) N (C (CN3CCOCC3) =O) CC2) (=C\4/C=5C (NC4=O) =CC (C (OC) =O) =CC5) /C6=CC=CC=C6
Molecular Formula
C31H30N4O5
Molecular Weight
538.59
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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