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LAS191859

LAS191859 is a potent and selective CRTH2 (DP2) antagonist with IC50 values in the low nanomolar range across species. Its exceptionally long receptor residence time (t1/2 ~21h) underpins durable in vivo efficacy, making it a valuable tool for investigating allergic inflammation models in both cellular and animal studies.

Product Specifications

CAS Number

1420071-13-1

Field of Research

Immunology & Inflammation, Pharmacology & Drug Discovery

Smiles

C (N (C (=O) C1CC1) CC) C2=C (N3C=4C (C (CC (O) =O) =C3) =CC=C (C) N4) C=CC (C (F) (F) F) =C2

Molecular Formula

C24H24F3N3O3

Molecular Weight

459.46

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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