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Lecozotan HCl

Lecozotan HCl (SRA-333) is a selective 5-HT1A receptor antagonist that potentiates KCl-evoked glutamate and acetylcholine release in the hippocampus, exhibiting pro-cognitive effects. Studies indicate its chronic use does not lead to receptor tolerance, supporting its research utility in neuropharmacology for cognitive disorders.

Product Specifications

CAS Number

433282-68-9

Product Name Alternative

SRA333, SRA-333, SRA 333, Lecozotan HCl, Lecozotan Hydrochloride, Lecozotan hydrochloride, 5-HT, 5HT Receptor, 5HTReceptor

Field of Research

Neuroscience, Pharmacology & Drug Discovery

Purity

99.04% (May vary between batches)

Solubility

DMSO:50 mg/mL (96.15 mM)

Smiles

[C@H] (CN (C (=O) C1=CC=C (C#N) C=C1) C2=CC=CC=N2) (C) N3CCN (C4=C5C (=CC=C4) OCCO5) CC3.Cl

Molecular Formula

C28H30ClN5O3

Molecular Weight

520.02

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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