Catharanthine

Catharanthine is a bioactive alkaloid that potently inhibits nicotinic acetylcholine receptor function, as demonstrated by its suppression of receptor-mediated diaphragm muscle contractions with an IC50 of 59.6 μM. This small molecule is a valuable research tool for studying cholinergic signaling and neuromuscular junction physiology in both in vitro and ex vivo experimental models.

Product Specifications

CAS Number

2468-21-5

Product Name Alternative

CalciumChannel, Ca channels, Ca2+ channels, Calcium Channel, Catharanthine, 3,4-Didehydrocoronaridine, 3, 4-Didehydrocoronaridine, (+) -3, 4-Didehydrocoronaridine, (+) -3,4-Didehydrocoronaridine, Inhibitor, inhibit, nAChR

Field of Research

Metabolism Research, Neuroscience, Pharmacology & Drug Discovery

Purity

99.11% (May vary between batches)

Solubility

H2O:< 1 mg/mL (insoluble or slightly soluble) ; Ethanol:1 mg/mL (2.97 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (9.81 mM) ; DMSO:40 mg/mL (118.9 mM)