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LY243246

LY249543, the S-enantiomer of lometrexol, is a potent and selective inhibitor of Methylenetetrahydrofolate Dehydrogenase/Cyclohydrolase (MTHFD2) . This compound is a valuable research tool for investigating folate metabolism in cancer biology, with applications in both in vitro enzymatic assays and in vivo tumor model studies.

Product Specifications

CAS Number

106400-18-4

Field of Research

Cell Biology

Smiles

O=C1C2=C (NC[C@@H] (CCC3=CC=C (C (N[C@@H] (CCC (O) =O) C (O) =O) =O) C=C3) C2) NC (N) =N1

Molecular Formula

C21H25N5O6

Molecular Weight

443.45

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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