Methotrexate monohydrate
Methotrexate monohydrate is a potent inhibitor of dihydrofolate reductase (DHFR), leading to suppressed T cell activation, reduced cytokine production, and enhanced T cell apoptosis. This small molecule is widely used in immunology and oncology research, with established applications in both in vitro cellular assays and in vivo models of autoimmune disease and inflammation.
Product Specifications
CAS Number
6745-93-3
Field of Research
Cell Biology, Infectious Disease & Virology, Molecular Biology, Pharmacology & Drug Discovery
Smiles
NC=1C2=C (N=CC (CN (C) C3=CC=C (C (N[C@@H] (CCC (O) =O) C (O) =O) =O) C=C3) =N2) N=C (N) N1.O
Molecular Formula
C20H24N8O6
Molecular Weight
472.45
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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