MMRi64
MMRi64 is a potent small molecule inhibitor of the Mdm2-MdmX E3 ligase complex, disrupting their interaction and leading to p53 stabilization and apoptosis in leukemia/lymphoma cells. It is a valuable research tool for studying p53 pathway reactivation in cancer, with applications in both in vitro and in vivo oncology models.
Product Specifications
CAS Number
430458-66-5
Product Name Alternative
P53, MMRi64, MMRi-64, Mdm2, MDMX, Apoptosis
Field of Research
Cell Biology
Purity
99.61% (May vary between batches)
Solubility
10% DMSO+90% Corn Oil:2.5 mg/mL (6.09 mM) ; DMSO:60 mg/mL (146.23 mM)
Smiles
C (NC1=CC (C) =CC=N1) (C2=C (O) C3=C (C=C2) C=CC=N3) C4=C (Cl) C (Cl) =CC=C4
Molecular Formula
C22H17Cl2N3O
Molecular Weight
410.3
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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