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MMRi64

MMRi64 is a potent small molecule inhibitor of the Mdm2-MdmX E3 ligase complex, disrupting their interaction and leading to p53 stabilization and apoptosis in leukemia/lymphoma cells. It is a valuable research tool for studying p53 pathway reactivation in cancer, with applications in both in vitro and in vivo oncology models.

Product Specifications

CAS Number

430458-66-5

Product Name Alternative

P53, MMRi64, MMRi-64, Mdm2, MDMX, Apoptosis

Field of Research

Cell Biology

Purity

99.61% (May vary between batches)

Solubility

10% DMSO+90% Corn Oil:2.5 mg/mL (6.09 mM) ; DMSO:60 mg/mL (146.23 mM)

Smiles

C (NC1=CC (C) =CC=N1) (C2=C (O) C3=C (C=C2) C=CC=N3) C4=C (Cl) C (Cl) =CC=C4

Molecular Formula

C22H17Cl2N3O

Molecular Weight

410.3

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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