MS453
MS453 is a potent and selective small-molecule inhibitor of the histone methyltransferase SETD8, exhibiting an IC50 of 804 nM. It serves as a valuable chemical probe for epigenetic research, enabling the study of histone H4 lysine 20 monomethylation (H4K20me1) in cellular and biochemical assays.
Product Specifications
CAS Number
2059892-29-2
Field of Research
Epigenetics & Chromatin
Smiles
N (CCCNC (C=C) =O) C=1C2=C (N=C (N1) N3CCCC3) C=C (OC) C (OC) =C2
Molecular Formula
C20H27N5O3
Molecular Weight
385.46
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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