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NSC668394

NSC668394 is a potent inhibitor of ezrin phosphorylation at Thr567, which suppresses its role in tumor metastasis. Its mechanism involves promoting Ca2+-dependent ezrin cleavage, demonstrating antitumor potential in cellular studies. This compound is a valuable tool for investigating cancer cell motility and invasion in vitro.

Product Specifications

CAS Number

382605-72-3

Product Name Alternative

NSC668394, NSC-668394, NSC 668394, PKC

Field of Research

Epigenetics & Chromatin, Signal Transduction

Purity

99.29% (May vary between batches)

Solubility

DMSO:30 mg/mL (66.36 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.42 mM)

Smiles

Oc1c (Br) cc (CCNC2=CC (=O) c3cccnc3C2=O) cc1Br

Molecular Formula

C17H12Br2N2O3

Molecular Weight

452.1

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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