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ONO-0300302

ONO-0300302 is a potent, slow tight-binding LPA1 receptor antagonist with an IC50 of 0.16 nM. It has demonstrated in vivo efficacy by significantly reducing LPA-induced increases in intraurethral pressure in both rat and dog models following oral administration, supporting its research application in urological studies such as benign prostatic hyperplasia.

Product Specifications

CAS Number

856689-51-5

Field of Research

Pharmacology & Drug Discovery

Smiles

COc1cc (cc (OC) c1C) [C@@H] (O) [C@@H] (CC1Cc2ccccc2C1) Cn1ccc (CCC (O) =O) c1

Molecular Formula

C29H35NO5

Molecular Weight

477.59

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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