ONO-0300302
ONO-0300302 is a potent, slow tight-binding LPA1 receptor antagonist with an IC50 of 0.16 nM. It has demonstrated in vivo efficacy by significantly reducing LPA-induced increases in intraurethral pressure in both rat and dog models following oral administration, supporting its research application in urological studies such as benign prostatic hyperplasia.
Product Specifications
CAS Number
856689-51-5
Field of Research
Pharmacology & Drug Discovery
Smiles
COc1cc (cc (OC) c1C) [C@@H] (O) [C@@H] (CC1Cc2ccccc2C1) Cn1ccc (CCC (O) =O) c1
Molecular Formula
C29H35NO5
Molecular Weight
477.59
Storage Conditions
-20°C
Notes
For research use only.
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