OSI-296
OSI-296 is a dual cMET and RON kinase inhibitor with IC50 values of 42 nM and 200 nM, respectively. It demonstrates oral efficacy and tolerability in xenograft models, including bone metastasis, making it a valuable research tool for studying oncogenic signaling pathways in vitro and in vivo.
Product Specifications
CAS Number
1175296-94-2
Field of Research
Cell Biology, Signal Transduction
Smiles
O ([C@H] (C) C1=C (Cl) C (F) =CC=C1Cl) C2=C3C (C (=CO3) C=4CCN (C (N) =O) CC4) =CN=C2N
Molecular Formula
C21H19Cl2FN4O3
Molecular Weight
465.3
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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