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OSI-296

OSI-296 is a dual cMET and RON kinase inhibitor with IC50 values of 42 nM and 200 nM, respectively. It demonstrates oral efficacy and tolerability in xenograft models, including bone metastasis, making it a valuable research tool for studying oncogenic signaling pathways in vitro and in vivo.

Product Specifications

CAS Number

1175296-94-2

Field of Research

Cell Biology, Signal Transduction

Smiles

O ([C@H] (C) C1=C (Cl) C (F) =CC=C1Cl) C2=C3C (C (=CO3) C=4CCN (C (N) =O) CC4) =CN=C2N

Molecular Formula

C21H19Cl2FN4O3

Molecular Weight

465.3

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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