PF-06827443
PF-06827443 is an orally administered, brain-penetrant positive allosteric modulator (PAM) that exhibits high selectivity for the M1 muscarinic acetylcholine receptor with negligible intrinsic agonist activity. It is a valuable research tool for investigating M1 receptor function in both in vitro assays and in vivo models relevant to cognitive disorders.
Product Specifications
Field of Research
Neuroscience
Smiles
O=C1N ([C@@H]2[C@@H] (O) COCC2) CC3=C1C=C (CC4=CC=C (C5=COC=N5) C=C4) C (C) =C3
Molecular Formula
C24H24N2O4
Molecular Weight
404.47
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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